z-logo
open-access-imgOpen Access
Association of OAZ1 Gene Polymorphisms With Subclinical and Clinical Vascular Events
Author(s) -
Julie Dumont,
Mahmoud Zureik,
Christophe Bauters,
Marie-Catherine Grupposo,
Dominique Cottel,
Michèle Montaye,
Martial Hamon,
Pierre Ducimetière,
Philippe Amouyel,
Thierry Brousseau
Publication year - 2007
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.107.150458
Subject(s) - allele , vascular smooth muscle , medicine , restenosis , biology , vascular disease , endocrinology , gene , genetics , stent , smooth muscle
Proliferation and migration of vascular smooth muscle cells (VSMCs) are striking features shared by vascular ageing, atherosclerosis, and in-stent restenosis. VSMC biology depends in part on polyamines whose metabolism is closely regulated by ornithine decarboxylase antizyme 1 (OAZ1). Therefore, we sought for association between OAZ1 gene polymorphisms and various outcomes involving VSMC proliferation.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom