Differential Effect of Hypolipidemic Drugs on Lipoprotein-Associated Phospholipase A 2
Author(s) -
Vasilios G. Saougos,
Afroditi P. Tambaki,
M. Kalogirou,
Michael S. Kostapanos,
Irene F. Gazi,
Robert L. Wolfert,
Moses Elisaf,
Alexandros D. Tselepis
Publication year - 2007
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.107.147280
Subject(s) - fenofibrate , lipoprotein associated phospholipase a2 , rosuvastatin , ezetimibe , medicine , endocrinology , apolipoprotein b , chemistry , lipoprotein , dyslipidemia , very low density lipoprotein , lipoprotein(a) , pharmacology , cholesterol , diabetes mellitus
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a predictor for incident atherosclerotic disease. We investigated the effect of 3 hypolipidemic drugs that exert their action through different mechanisms on plasma and lipoprotein-associated Lp-PLA2 activity and mass.
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