Preferential Sphingosine-1-Phosphate Enrichment and Sphingomyelin Depletion Are Key Features of Small Dense HDL3 Particles | Zendy

Anatol Kontush | Zendy; Patrice Thérond | Zendy; Amal Zerrad-Saadi | Zendy; Martine Couturier | Zendy; Anne NègreSalvayre | Zendy; Juliana Aparecida Souza | Zendy; Sandrine Chantepie | Zendy; M. John Chapman | Zendy

Open Access

Preferential Sphingosine-1-Phosphate Enrichment and Sphingomyelin Depletion Are Key Features of Small Dense HDL3 Particles

Author(s) -

Anatol Kontush,

Patrice Thérond,

Amal Zerrad-Saadi,

Martine Couturier,

Anne NègreSalvayre,

Juliana Aparecida Souza,

Sandrine Chantepie,

M. John Chapman

Publication year - 2007

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.107.145672

Subject(s) - sphingomyelin , sphingosine , chemistry , sphingolipid , ceramide , biochemistry , sphingosine 1 phosphate , phosphate , lipid signaling , cholesterol , enzyme , apoptosis , receptor

The purpose of this study was to define heterogeneity in the molecular profile of lipids, including sphingomyelin and sphingosine-1-phosphate, among physicochemically-defined HDL subpopulations and potential relevance to antiatherogenic biological activities of dense HDL3.

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