Open AccessChronic Immune Reactivity Against Persisting Microbial Antigen in the Vasculature Exacerbates Atherosclerotic Lesion Formation
Author(s) -
Philippe Krebs,
Elke Scandella,
Beatrice Bolinger,
Daniel Engeler,
Simone Miller,
Burkhard Ludewig
Publication year - 2007
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.107.141846
Subject(s) - immune system , lesion , antigen , medicine , reactivity (psychology) , pathology , antigen antibody complex , immunology , alternative medicine
The purpose of this study was to examine the relative contribution of different immunopathological mechanisms during murine cytomegalovirus (MCMV)-mediated acceleration of atheroma formation in apolipoprotein E-deficient (apoE-/-) mice.
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