Preservation of Rabbit Aorta Elastin From Degradation by Gingival Fibroblasts in an Ex Vivo Model
Author(s) -
Bruno Gogly,
Adrien Naveau,
Benjamin Fournier,
Nicoleta Reinald,
Éric Durand,
Camille Brasselet,
Bernard Coulomb,
Antoine Lafont
Publication year - 2007
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.107.140640
Subject(s) - elastin , ex vivo , rabbit (cipher) , in vivo , aorta , chemistry , pathology , medicine , biology , microbiology and biotechnology , statistics , mathematics
Embryo-like gingival healing properties are attributed to the gingival fibroblast (GF) and could be used as a model for other types of healing dysfunctions. Abdominal aortic aneurysm (AAA) formation is associated with elastin degradation and increase in matrix metalloproteinase (MMP)-9 activity. We aimed to validate the concept of using GF healing properties in arteries.
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