Oxysterol Binding Protein Induces Upregulation of SREBP-1c and Enhances Hepatic Lipogenesis | Zendy

Daoguang Yan | Zendy; Markku Lehto | Zendy; Laura Rasilainen | Zendy; Jari Metso | Zendy; Christian Ehnholm | Zendy; Seppo YläHerttuala | Zendy; Matti Jauhiainen | Zendy; Vesa M. Olkkonen | Zendy

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Oxysterol Binding Protein Induces Upregulation of SREBP-1c and Enhances Hepatic Lipogenesis

Author(s) -

Daoguang Yan,

Markku Lehto,

Laura Rasilainen,

Jari Metso,

Christian Ehnholm,

Seppo YläHerttuala,

Matti Jauhiainen,

Vesa M. Olkkonen

Publication year - 2007

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.106.138545

Subject(s) - oxysterol , lipogenesis , downregulation and upregulation , sterol regulatory element binding protein , chemistry , microbiology and biotechnology , medicine , biology , biochemistry , cholesterol , lipid metabolism , sterol , gene

Oxysterol binding protein (OSBP) has previously been implicated as a sterol sensor that regulates sphingomyelin synthesis and the activity of extracellular signal-regulated kinases (ERK).

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