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Controlled trial of ornithine alpha ketoglutarate (OAKG) in patients with stroke.
Author(s) -
M. L. Woollard,
Rahel Pearson,
G Dorf,
Daniel Griffith,
I. M. James
Publication year - 1978
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.9.3.218
Subject(s) - medicine , stroke (engine) , alpha (finance) , clinical trial , ornithine , randomized controlled trial , surgery , pediatrics , patient satisfaction , biochemistry , mechanical engineering , construct validity , chemistry , amino acid , arginine , engineering
A double blind controlled trial of ornithine alpha-ketoglutarate (OAKG) was carried out on 50 patients admitted to the Royal Free and Royal Northern Hospitals, London, suffering from a recent stroke. Significant improvement was found in patients treated with OAKG when examined on the fifth day of therapy as compared to their control cases. The therapy was given for 5 days. When the patients in the treated and the control groups were compared 10 days after the beginning of treatment, there were no differences between the 2 groups. Implications of these findings are discussed.

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