Xenon enhanced CT for analysis of cerebral integrity, perfusion, and blood flow. | Zendy

Burton P. Drayer | Zendy; Sidney K. Wolfson | Zendy; O. M. Reinmuth | Zendy; Manuel Dujovny | Zendy; Manfred Boehnke | Zendy; E.E. Cook | Zendy

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Xenon enhanced CT for analysis of cerebral integrity, perfusion, and blood flow.

Author(s) -

Burton P. Drayer,

Sidney K. Wolfson,

O. M. Reinmuth,

Manuel Dujovny,

Manfred Boehnke,

E.E. Cook

Publication year - 1978

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.9.2.123

Subject(s) - medicine , cerebral blood flow , xenon , baboon , cerebral perfusion pressure , perfusion , blood flow , cerebrovascular circulation , nuclear medicine , perfusion scanning , cardiology , physics , atomic physics

Enhancement of the brain substance for CT evaluation using inhaled Xenon is confirmed. This technique was applied to the study of the normal and the embolized adolescent baboon. Healthy cerebral tissue enhances symmetrically, while abnormal areas show significantly diminished enhancement. At maximal enhancement, an indication of gross comparative cerebral perfusion to obtained. By obtaining serial CT scans over a 10 minute time interval, the clearance rate of Xenon (cerebral blood flow) may be evaluated. Xenon-enhanced CT enables a visual and numerical analysis of both brain morphology and physiology.

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