Therapy Against Brain Swelling in Stroke Patients | Zendy

L. Candelise | Zendy; Alvaro Colombo | Zendy; Hans Spinnler | Zendy

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Therapy Against Brain Swelling in Stroke Patients

Author(s) -

L. Candelise,

Alvaro Colombo,

Hans Spinnler

Publication year - 1975

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.6.4.353

Subject(s) - medicine , dexamethasone , stroke (engine) , swelling , brain swelling , cerebral edema , anesthesia , mannitol , brain edema , surgery , pathology , mechanical engineering , chemistry , organic chemistry , engineering

The effectiveness of cerebral antiedema agents in stroke has been questioned. Animal and clinical work is inconclusive about steroids and osmotic drugs. A retrospective study of a continuous series of 227 stroke patients treated in the acute stage (some with dexamethasone alone, some with dexamethasone plus hyperosmotic mannitol infusions, and some without antiedema therapy) showed no significant difference in the ten-day survival rate. On this criterion, there is no ground for the systematic use of such agents against this type of brain swelling.

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