A Comparison of Betahistine Hydrochloride With Placebo for Vertebral-Basilar Insufficiency: A Double-Blind Study | Zendy

JAMES H. SPRUILL | Zendy; James F. Toole | Zendy; William Kitto | Zendy; Hersey E. Miller | Zendy

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A Comparison of Betahistine Hydrochloride With Placebo for Vertebral-Basilar Insufficiency: A Double-Blind Study

Author(s) -

JAMES H. SPRUILL,

James F. Toole,

William Kitto,

Hersey E. Miller

Publication year - 1975

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.6.2.116

Subject(s) - medicine , betahistine , placebo , basilar artery , anesthesia , vertebral artery , vertigo , surgery , alternative medicine , pathology

To test the effectiveness of betahistine HCl in reducing the frequency of transient ischemic attacks (TIAs) caused by vertebral-basilar artery insufficiency, we randomly assigned 26 patients with a typical history of the condition to a placebo-drug or a drug-placebo sequence, each sequence lasting two months. During the study, the frequency of TIAs did not differ significantly between the placebo and the drug groups. Subjective responses indicated some value for betahistine as a palliative agent.

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