Cerebral Protection During Carotid Endarterectomy
Author(s) -
J. Howe,
Glenn W. Kindt
Publication year - 1974
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.5.3.340
Subject(s) - medicine , carotid endarterectomy , anesthesia , cerebral blood flow , shunt (medical) , regimen , blood pressure , oxygen tension , cardiology , carotid arteries , oxygen , chemistry , organic chemistry
Carotid endarterectomy was performed on 73 occasions using the following regimen during the operative period: (1) general anesthesia with normothermia, (2) maintaining a normal or slightly elevated arterial oxygen tension (Pao2, (3) maintaining a normal or low arterial carbon dioxide tension (Pco2), (4) maintaining systemic arterial pressure (SAP) at normal or slightly elevated levels, (5) employing a bypass shunt in all cases, and (6) utilizing transient systemic anticoagulation with heparin. The rationale for this regimen is explained in terms of current concepts of cerebral blood flow and metabolism. No new neurological deficit has appeared after operation using these techniques.
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