Effect of Anoxia on Protein Metabolism in Subcellular Fractions of Rabbit Brain | Zendy

Takehiko Yanagihara | Zendy

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Effect of Anoxia on Protein Metabolism in Subcellular Fractions of Rabbit Brain

Author(s) -

Takehiko Yanagihara

Publication year - 1974

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.5.2.226

Subject(s) - leucine , microsome , metabolism , in vitro , biochemistry , medicine , cerebral anoxia , rabbit (cipher) , protein metabolism , protein biosynthesis , lagomorpha , amino acid , biology , statistics , mathematics

The effect of cerebral anoxia on leucine incorporation into proteins of various subcellular fractions from rabbit brain was studied by using a previously reported in vitro model. Although the decrease in leucine incorporation was observed earlier in nuclei and microsomes, other fractions also demonstrated a rapid decrease. These results were quite different from the pattern of leucine incorporation observed in a type of reversible suppression produced with diphenylhydantoin.

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