Enhanced Endothelium-Dependent Vasodilation in Fabry Disease | Zendy

Gheona Altarescu | Zendy; David F. Moore | Zendy; Randall Pursley | Zendy; Umberto Campia | Zendy; Seth R. Goldstein | Zendy; Melissa B. Bryant | Zendy; Julio A. Panza | Zendy; Raphael Schiffmann | Zendy

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Enhanced Endothelium-Dependent Vasodilation in Fabry Disease

Author(s) -

Gheona Altarescu,

David F. Moore,

Randall Pursley,

Umberto Campia,

Seth R. Goldstein,

Melissa B. Bryant,

Julio A. Panza,

Raphael Schiffmann

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.32.7.1559

Subject(s) - medicine , vasodilation , fabry disease , cardiology , endothelium , stroke (engine) , fabry's disease , disease , mechanical engineering , engineering

Fabry disease is an X-linked lysosomal storage disease secondary to deficiency of alpha-galactosidase A with resulting glycolipid accumulation, particularly globotriaosylceramide in arterial smooth muscle and endothelial cells. A systemic vasculopathy, including early-onset stroke, is prevalent without a clear pathogenesis.

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