A New Rating Scale for Age-Related White Matter Changes Applicable to MRI and CT | Zendy

LarsOlof Wahlund | Zendy; Frederik Barkhof | Zendy; Franz Fazekas | Zendy; Lena Bronge | Zendy; Michael Augustin | Zendy; Magnus Sjögren | Zendy; Anders Wallin | Zendy; H.J. Adèr | Zendy; Didier Leys | Zendy; Leonardo Pantoni | Zendy; Florence Pasquier | Zendy; Timo Erkinjuntti | Zendy; Philip Scheltens | Zendy

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A New Rating Scale for Age-Related White Matter Changes Applicable to MRI and CT

Author(s) -

LarsOlof Wahlund,

Frederik Barkhof,

Franz Fazekas,

Lena Bronge,

Michael Augustin,

Magnus Sjögren,

Anders Wallin,

H.J. Adèr,

Didier Leys,

Leonardo Pantoni,

Florence Pasquier,

Timo Erkinjuntti,

Philip Scheltens

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.32.6.1318

Subject(s) - medicine , magnetic resonance imaging , inter rater reliability , neuroimaging , radiology , rating scale , nuclear medicine , psychology , psychiatry , developmental psychology

MRI is more sensitive than CT for detection of age-related white matter changes (ARWMC). Most rating scales estimate the degree and distribution of ARWMC either on CT or on MRI, and they differ in many aspects. This makes it difficult to compare CT and MRI studies. To be able to study the evolution and possible effect of drug treatment on ARWMC in large patient samples, it is necessary to have a rating scale constructed for both MRI and CT. We have developed and evaluated a new scale and studied ARWMC in a large number of patients examined with both MRI and CT.

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