A Modified National Institutes of Health Stroke Scale for Use in Stroke Clinical Trials | Zendy

Patrick D. Lyden | Zendy; Mei Lü | Zendy; Steven R. Levine | Zendy; Thomas Brott | Zendy; Joseph P. Broderick | Zendy

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A Modified National Institutes of Health Stroke Scale for Use in Stroke Clinical Trials

Author(s) -

Patrick D. Lyden,

Mei Lü,

Steven R. Levine,

Thomas Brott,

Joseph P. Broderick

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.32.6.1310

Subject(s) - medicine , stroke (engine) , physical therapy , physical medicine and rehabilitation , clinical trial , thrombolysis , ceiling effect , reliability (semiconductor) , odds ratio , alternative medicine , pathology , mechanical engineering , power (physics) , physics , quantum mechanics , myocardial infarction , engineering

The National Institutes of Health Stroke Scale (NIHSS) is accepted widely for measuring acute stroke deficits in clinical trials, but it contains items that exhibit poor reliability or do not contribute meaningful information. To improve the scale for use in clinical research, we used formal clinimetric analyses to derive a modified version, the mNIHSS. We then sought to demonstrate the validity and reliability of the new mNIHSS.

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