Enhanced Expression of Iba1, Ionized Calcium-Binding Adapter Molecule 1, After Transient Focal Cerebral Ischemia In Rat Brain | Zendy

Daisuke Ito | Zendy; Kortaro Tanaka | Zendy; Shigeaki Suzuki | Zendy; Tomohisa Dembo | Zendy; Yasuo Fukuuchi | Zendy

Open Access

Enhanced Expression of Iba1, Ionized Calcium-Binding Adapter Molecule 1, After Transient Focal Cerebral Ischemia In Rat Brain

Author(s) -

Daisuke Ito,

Kortaro Tanaka,

Shigeaki Suzuki,

Tomohisa Dembo,

Yasuo Fukuuchi

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.32.5.1208

Subject(s) - microglia , immunostaining , medicine , ischemia , pathology , downregulation and upregulation , middle cerebral artery , immunohistochemistry , brain ischemia , neuroscience , inflammation , biology , biochemistry , gene

Iba1 is a novel calcium-binding protein and is specifically expressed in microglia in the brain. It has been suggested that Iba1 plays an important role in regulation of the function of microglia. In the present study we examined time-dependent Iba1 expression after transient middle cerebral artery occlusion and characterized microglial activation in various brain regions.

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