Temporal Relationship Between Endothelin-1 Concentrations and Cerebral Vasospasm in Patients With Aneurysmal Subarachnoid Hemorrhage | Zendy

Luciana Mascia | Zendy; Ludwik Fedorko | Zendy; Duncan J. Stewart | Zendy; Farida Mohamed | Zendy; Karel G. terBrugge | Zendy; V. Marco Ranieri | Zendy; M. Christopher Wallace | Zendy

Open Access

Temporal Relationship Between Endothelin-1 Concentrations and Cerebral Vasospasm in Patients With Aneurysmal Subarachnoid Hemorrhage

Author(s) -

Luciana Mascia,

Ludwik Fedorko,

Duncan J. Stewart,

Farida Mohamed,

Karel G. terBrugge,

V. Marco Ranieri,

M. Christopher Wallace

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.32.5.1185

Subject(s) - medicine , subarachnoid hemorrhage , vasospasm , cerebral vasospasm , endothelin receptor , cardiology , endothelin 1 , anesthesia , receptor

Endothelin 1 (ET-1) is a potent vasoconstrictor that may play a role in cerebral vasospasm following subarachnoid hemorrhage (SAH). However, data regarding its pathogenic role in the development of vasospasm are controversial. We planned a prospective, observational clinical study to investigate the temporal relationship between increased ET-1 production and cerebral vasospasm or other neurological sequelae after SAH.

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