Viability Thresholds of Ischemic Penumbra of Hyperacute Stroke Defined by Perfusion-Weighted MRI and Apparent Diffusion Coefficient
Author(s) -
Lisbeth Røhl,
Leif Østergaard,
Claus Z. Simonsen,
Peter VestergaardPoulsen,
Grethe Andersen,
Masaharu Sakoh,
Denis Le Bihan,
Carsten Gyldensted
Publication year - 2001
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.32.5.1140
Subject(s) - penumbra , medicine , effective diffusion coefficient , nuclear medicine , perfusion , infarction , cerebral blood flow , stroke (engine) , region of interest , cerebral infarction , radiology , ischemia , magnetic resonance imaging , cardiology , myocardial infarction , mechanical engineering , engineering
The penumbra of ischemic stroke consists of hypoperfused, but not irreversibly damaged, tissue surrounding the ischemic core. The purpose of this study was to determine viability thresholds in the ischemic penumbra, defined as the perfusion/diffusion mismatch in hyperacute stroke, by the use of diffusion- and perfusion-weighted MRI (DWI and PWI, respectively).
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