Insulin Resistance and Elevated Levels of Tissue Plasminogen Activator in First-Degree Relatives of South Asian Patients With Ischemic Cerebrovascular Disease
Author(s) -
Kirti Kain,
Andrew J. Catto,
Duncan Young,
John Bamford,
John Bavington,
Peter J. Grant
Publication year - 2001
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.32.5.1069
Subject(s) - medicine , diabetes mellitus , insulin resistance , stroke (engine) , body mass index , family history , plasminogen activator , first degree relatives , vascular disease , insulin , disease , risk factor , endocrinology , gastroenterology , mechanical engineering , engineering
South Asians in the United Kingdom suffer from an increased mortality from cerebrovascular disease compared with whites. Evidence suggests that the relatives of white stroke patients are at increased risk of vascular disease. The aim of this study was to investigate atherothrombotic risk factors in the first-degree relatives of South Asian patients suffering from ischemic cerebrovascular disease and to compare them with South Asian subjects free from clinically detectable cerebrovascular disease.
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