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A Model for Multiparametric MRI Tissue Characterization in Experimental Cerebral Ischemia With Histological Validation in Rat
Author(s) -
Michael A. Jacobs,
Zheng G. Zhang,
Robert A. Knight,
Hamid SoltanianZadeh,
Anton Goussev,
Donald J. Peck,
Michael Chopp
Publication year - 2001
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.32.4.943
Subject(s) - medicine , diffusion mri , ischemia , brain tissue , multiparametric mri , data set , stroke (engine) , segmentation , ischemic stroke , pathology , biomedical engineering , magnetic resonance imaging , radiology , artificial intelligence , prostate , computer science , mechanical engineering , cancer , engineering
After stroke, brain tissue undergoes time-dependent heterogeneous histopathological change. These tissue alterations have MRI characteristics that allow segmentation of ischemic from nonischemic tissue. Moreover, MRI segmentation generates different zones within the lesion that may reflect heterogeneity of tissue damage.

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