Molecular Anatomy of an Intracranial Aneurysm | Zendy

David G. Peters | Zendy; Amin Kassam | Zendy; Eleanor Feingold | Zendy; Elisa Heidrich-O’Hare | Zendy; Howard Yonas | Zendy; Robert E. Ferrell | Zendy; Adam Brufsky | Zendy

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Molecular Anatomy of an Intracranial Aneurysm

Author(s) -

David G. Peters,

Amin Kassam,

Eleanor Feingold,

Elisa Heidrich-O’Hare,

Howard Yonas,

Robert E. Ferrell,

Adam Brufsky

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.32.4.1036

Subject(s) - aneurysm , medicine , extracellular matrix , subarachnoid hemorrhage , pathology , elastin , bioinformatics , radiology , biology , genetics , surgery

Approximately 6% of human beings harbor an unruptured intracranial aneurysm. Each year in the United States, >30 000 people suffer a ruptured intracranial aneurysm, resulting in subarachnoid hemorrhage. Despite the high incidence and catastrophic consequences of a ruptured intracranial aneurysm and the fact that there is considerable evidence that predisposition to intracranial aneurysm has a strong genetic component, very little is understood with regard to the pathology and pathogenesis of this disease.

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