Very Early Nimodipine Use in Stroke (VENUS) | Zendy

Janneke Horn | Zendy; Rob J. de Haan | Zendy; M. Vermeulen | Zendy; M. Limburg | Zendy

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Very Early Nimodipine Use in Stroke (VENUS)

Author(s) -

Janneke Horn,

Rob J. de Haan,

M. Vermeulen,

M. Limburg

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.32.2.461

Subject(s) - nimodipine , medicine , placebo , stroke (engine) , anesthesia , interim analysis , adverse effect , subgroup analysis , randomized controlled trial , meta analysis , mechanical engineering , alternative medicine , pathology , engineering , calcium

The Very Early Nimodipine Use in Stroke (VENUS) trial was designed to test the hypothesis that early treatment with nimodipine has a positive effect on survival and functional outcome after stroke. This was suggested in a previous meta-analysis on the use of nimodipine in stroke. However, in a recent Cochrane review we were unable to reproduce these positive results. This led to the early termination of VENUS after an interim analysis.

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