Risk Factors for Severe Hemorrhagic Transformation in Ischemic Stroke Patients Treated With Recombinant Tissue Plasminogen Activator | Zendy

Vincent Larrue | Zendy; Rüdiger von Kummer | Zendy; Achim Müller | Zendy; Erich Bluhmki | Zendy

Open Access

Risk Factors for Severe Hemorrhagic Transformation in Ischemic Stroke Patients Treated With Recombinant Tissue Plasminogen Activator

Author(s) -

Vincent Larrue,

Rüdiger von Kummer,

Achim Müller,

Erich Bluhmki

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.32.2.438

Subject(s) - medicine , thrombolysis , intracerebral hemorrhage , stroke (engine) , aspirin , cardiology , tissue plasminogen activator , surgery , myocardial infarction , subarachnoid hemorrhage , mechanical engineering , engineering

Intravenous thrombolysis with recombinant tissue plasminogen activator (rtPA) improves the outcome for ischemic stroke patients who can be treated within 3 hours of symptom onset. The efficacy of thrombolysis has been demonstrated despite an increased risk of severe hemorrhagic transformation (HT) in patients treated with rtPA. We performed an analysis of risk factors for severe HT in the second European-Australasian Acute Stroke Study (ECASS II).

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