Quantitative Assessment of the Ischemic Brain by Means of Perfusion-Related Parameters Derived From Perfusion CT | Zendy

M. Glenn Koenig | Zendy; Michael A. Kraus | Zendy; Carmen Theek | Zendy; Ernst Klotz | Zendy; Walter Gehlen | Zendy; L. Heuser | Zendy

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Quantitative Assessment of the Ischemic Brain by Means of Perfusion-Related Parameters Derived From Perfusion CT

Author(s) -

M. Glenn Koenig,

Michael A. Kraus,

Carmen Theek,

Ernst Klotz,

Walter Gehlen,

L. Heuser

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.32.2.431

Subject(s) - medicine , perfusion , cerebral blood flow , infarction , ischemia , perfusion scanning , cardiology , hemodynamics , cerebral perfusion pressure , nuclear medicine , radiology , myocardial infarction

Besides the delineation of hypoperfused brain tissue, the characterization of ischemia with respect to severity is of major clinical relevance, because the degree of hypoperfusion is the most critical factor in determining whether an ischemic lesion becomes an infarct or represents viable brain tissue. CT perfusion imaging yields a set of perfusion related parameters which might be useful to describe the hemodynamic status of the ischemic brain. Our objective was to determine whether measurements of the relative cerebral blood flow (rCBF), relative cerebral blood volume (rCBV), and relative time to peak (rTP) can be used to differentiate areas undergoing infarction from reversible ischemic tissue.

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