Inhibition of Poly(ADP-Ribose) Polymerase Attenuates Cerebral Vasospasm After Subarachnoid Hemorrhage in Rabbits | Zendy

Motoyoshi Satoh | Zendy; Isao Date | Zendy; Masaaki Nakajima | Zendy; Kenji Takahashi | Zendy; Keiichi Iseda | Zendy; Takashi Tamiya | Zendy; Takashi Ohmoto | Zendy; Yoshifumi Ninomiya | Zendy; Shoji Asari | Zendy

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Inhibition of Poly(ADP-Ribose) Polymerase Attenuates Cerebral Vasospasm After Subarachnoid Hemorrhage in Rabbits

Author(s) -

Motoyoshi Satoh,

Isao Date,

Masaaki Nakajima,

Kenji Takahashi,

Keiichi Iseda,

Takashi Tamiya,

Takashi Ohmoto,

Yoshifumi Ninomiya,

Shoji Asari

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.32.1.225

Subject(s) - medicine , subarachnoid hemorrhage , vasospasm , cerebral vasospasm , cisterna magna , basilar artery , anesthesia , lumen (anatomy) , h&e stain , vasoconstriction , parp inhibitor , pathology , poly adp ribose polymerase , immunohistochemistry , cerebrospinal fluid , polymerase , biology , biochemistry , gene

Poly(ADP-ribose) polymerase (PARP) is important in modulating inflammation, which has been implicated in cerebral vasospasm after subarachnoid hemorrhage (SAH). We investigated the role of PARP in vasospasm using 3-aminobenzamide (3-AB), a PARP inhibitor, in a rabbit model.

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