Role of Potassium Channels in Regulation of Brain Arteriolar Tone | Zendy

Tetsuyoshi Horiuchi | Zendy; Hans H. Dietrich | Zendy; Shinichiro Tsugane | Zendy; Ralph G. Dacey | Zendy

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Role of Potassium Channels in Regulation of Brain Arteriolar Tone

Author(s) -

Tetsuyoshi Horiuchi,

Hans H. Dietrich,

Shinichiro Tsugane,

Ralph G. Dacey

Publication year - 2001

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.32.1.218

Subject(s) - arteriole , potassium channel , medicine , tetraethylammonium , potassium channel blocker , cerebral arteries , potassium , nitric oxide , anatomy , microcirculation , inward rectifier potassium ion channel , anesthesia , endocrinology , chemistry , ion channel , organic chemistry , receptor

Potassium channels are important regulators of resting tone in large cerebral arteries, but their activity and distribution may vary according to vessel location and species studied. In the cerebral microcirculation in vivo, however, these channels appear to be silent at rest. Our goal was to determine the activity of potassium channels of brain arterioles from 2 origins under basal conditions in vitro.

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