Open AccessSystemic Complement Depletion Diminishes Perihematomal Brain Edema in Rats
Author(s) -
Guohua Xi,
Ya Hua,
Richard F. Keep,
John G. Younger,
Julian T. Hoff
Publication year - 2001
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.32.1.162
Subject(s) - medicine , edema , complement system , saline , western blot , pathology , endocrinology , pharmacology , immunology , antibody , chemistry , biochemistry , gene
The complement cascade is activated after experimental intracerebral hemorrhage (ICH). It remains unclear, however, whether depleting the complement system will improve injury resulting from ICH. This study investigated the effects of systemic complement depletion on brain edema formation after ICH.
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