Open AccessHydroxyethyl Starch Reduces Leukocyte Adherence and Vascular Injury in the Newborn Pig Cerebral Circulation After Asphyxia
Author(s) -
Stuart S. Kaplan,
T. S. Park,
Ernesto R. Gonzales,
Jeffrey M. Gidday
Publication year - 2000
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.31.9.2218
Subject(s) - medicine , hydroxyethyl starch , anesthesia , asphyxia , ischemia , vascular permeability , hematocrit
Hydroxyethyl starch (HES) has beneficial effects on ischemic brain injury; however, its mechanism of action remains unclear. The present study was undertaken to test the hypothesis that HES can attenuate increases in leukocyte adherence and vascular permeability in the cerebral vasculature after global cerebral ischemia induced by asphyxia.
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