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Impact of White Matter Changes on Clinical Manifestation of Alzheimer’s Disease
Author(s) -
Nobutsugu Hirono,
Hajime Kitagaki,
Hiroaki Kazui,
Mamoru Hashimoto,
Etsuro Mori
Publication year - 2000
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.31.9.2182
Subject(s) - medicine , disease , white matter , alzheimer's disease , stroke (engine) , pathology , magnetic resonance imaging , radiology , mechanical engineering , engineering
There have been conflicting results involving the clinical significance of white matter changes in patients with Alzheimer's disease (AD). We studied the association between the volume of white matter hyperintensities (WMHs) on T2-weighted images and cognitive, neurological, and neuropsychiatric symptoms.

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