Apolipoprotein E Polymorphism | Zendy

Mark Schiefermeier | Zendy; H. Kollegger | Zendy; Christian Madl | Zendy; Ch. Schwarz | Zendy; Michael Hölzer | Zendy; Julia Kofler | Zendy; Fritz Sterz | Zendy

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Apolipoprotein E Polymorphism

Author(s) -

Mark Schiefermeier,

H. Kollegger,

Christian Madl,

Ch. Schwarz,

Michael Hölzer,

Julia Kofler,

Fritz Sterz

Publication year - 2000

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.31.9.2068

Subject(s) - apolipoprotein e , medicine , genotype , odds ratio , cardiopulmonary resuscitation , logistic regression , epidemiology , surgery , resuscitation , disease , biology , genetics , gene

The apolipoprotein E 3/3 (apoE 3/3) genotype is associated with a reduced risk of developing Alzheimer's disease and with a favorable neurological outcome after traumatic head injury. In vitro studies suggest that the most common genotype, apoE 3/3, may be involved in neuroprotective and neuroregenerative mechanisms. The aim of this study was to determine whether the apoE 3/3 genotype has an impact on survival and neurological outcome after cardiopulmonary resuscitation.

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