Oxidative Stress in the Context of Acute Cerebrovascular Stroke
Author(s) -
Mohsen Muhammad Hussein El Kossi,
Madeha M. Zakhary
Publication year - 2000
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.31.8.1889
Subject(s) - medicine , ascorbic acid , lipid peroxide , superoxide dismutase , oxidative stress , nitric oxide , endocrinology , stroke (engine) , endothelial dysfunction , superoxide , homocysteine , antioxidant , biochemistry , chemistry , enzyme , mechanical engineering , food science , engineering
Free radical generation and consequent oxidative stress in thrombotic cerebrovascular stroke have a distinctive role in the pathogenesis of ischemic brain injury. One of the potential injurious effects of homocyst(e)ine in occlusive vascular diseases is free radical generation. In the current study, we investigated the status of oxidant stress in the acute phase of thrombotic cerebrovascular stroke and the possible role of homocyst(e)ine.
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