Open AccessThe N -Methyl- d -Aspartate Antagonist CNS 1102 Protects Cerebral Gray and White Matter From Ischemic Injury Following Temporary Focal Ischemia in Rats
Author(s) -
Wolf-R. Schäbitz,
Fuhai Li,
Marc Fisher
Publication year - 2000
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.31.7.1709
Subject(s) - medicine , antagonist , ischemia , white matter , anesthesia , brain ischemia , cardiology , magnetic resonance imaging , receptor , radiology
Cerebral white matter is as sensitive as gray matter to ischemic injury and is probably amenable to pharmacological intervention. In this study we investigated whether an N-methyl-D-aspartate (NMDA) antagonist, CNS 1102, protects not only cerebral gray matter but also white matter from ischemic injury.
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