MRI Measures of Middle Cerebral Artery Diameter in Conscious Humans During Simulated Orthostasis | Zendy

Jorge M. Serrador | Zendy; Paul A. Picot | Zendy; Brian K. Rutt | Zendy; J. Kevin Shoemaker | Zendy; Roberta L. Bondar | Zendy

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MRI Measures of Middle Cerebral Artery Diameter in Conscious Humans During Simulated Orthostasis

Author(s) -

Jorge M. Serrador,

Paul A. Picot,

Brian K. Rutt,

J. Kevin Shoemaker,

Roberta L. Bondar

Publication year - 2000

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.31.7.1672

Subject(s) - normocapnia , hypocapnia , hypercapnia , medicine , middle cerebral artery , anesthesia , cerebral blood flow , transcranial doppler , cardiology , ischemia , acidosis

The relationship between middle cerebral artery (MCA) flow velocity (CFV) and cerebral blood flow (CBF) is uncertain because of unknown vessel diameter response to physiological stimuli. The purpose of this study was to directly examine the effect of a simulated orthostatic stress (lower body negative pressure [LBNP]) as well as increased or decreased end-tidal carbon dioxide partial pressure (P(ET)CO(2)) on MCA diameter and CFV.

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