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Memory Impairment in Out-of-Hospital Cardiac Arrest Survivors Is Associated With Global Reduction in Brain Volume, Not Focal Hippocampal Injury
Author(s) -
Neil R. Grubb,
Keith A.A. Fox,
Karen Bulmer Smith,
Jonathan Best,
Annette Blane,
Klaus P. Ebmeier,
Michael F. Glabus,
Ronan E. O’Carroll
Publication year - 2000
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.31.7.1509
Subject(s) - medicine , hippocampal formation , memory impairment , cardiology , brain size , radiology , magnetic resonance imaging , psychiatry , cognition
More than 30% of out-of-hospital cardiac arrest (OHCA) survivors suffer significant memory impairment. The hippocampus may be vulnerable to hypoxic injury during cardiac arrest. The purpose of this study was to determine whether selective hippocampal injury is the substrate for this memory impairment.

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