Trials of Thrombolysis in Acute Ischemic Stroke | Zendy

Joanna M. Wardlaw | Zendy; Peter Sandercock | Zendy; Charles Warlow | Zendy; Richard I. Lindley | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Trials of Thrombolysis in Acute Ischemic Stroke

Author(s) -

Joanna M. Wardlaw,

Peter Sandercock,

Charles Warlow,

Richard I. Lindley

Publication year - 2000

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.31.5.1133

Subject(s) - thrombolysis , medicine , modified rankin scale , stroke (engine) , clinical trial , randomized controlled trial , fibrinolytic agent , outcome (game theory) , acute stroke , physical therapy , tissue plasminogen activator , physical medicine and rehabilitation , intensive care medicine , ischemic stroke , ischemia , myocardial infarction , mechanical engineering , mathematics , mathematical economics , engineering

Controversy regarding the risks and benefits of thrombolysis has not been helped by the perception that some trials were "positive" and others "negative" on their primary outcome measure of either "good" or "poor" functional outcome. We wondered whether the definition of good or poor functional outcome might have contributed to this perception, and what effect altering the definition might have on the individual trials and on the systematic review of all the trials combined.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research