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Plasma Endothelin-1 Levels Neither Increase nor Correlate With Neurological Scores, Stroke Risk Factors, or Outcome in Patients With Ischemic Stroke
Author(s) -
Elena Haapaniemi,
Turgut Tatlisumak,
K. Hamel,
Lauri Soinne,
Carmine Lanni,
Terry J. Opgenorth,
Markku Kaste
Publication year - 2000
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.31.3.720
Subject(s) - medicine , stroke (engine) , etiology , endothelins , body mass index , risk factor , prospective cohort study , ischemic stroke , endothelin 1 , pathophysiology , ischemia , mechanical engineering , engineering , receptor
Endothelins (ETs) are potent vasoconstrictors and may play a role in the pathophysiology of several diseases. Limited and controversial data exist on their role in human ischemic stroke. We planned a prospective, observational, and longitudinal clinical study to test whether ET-1 levels increase in various phases of ischemic stroke and whether the ET-1 levels correlate with neurological scores, stroke etiology, stroke risk factors, or final outcome.

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