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Oxidant stress, especially in the premature, plays a major role in the pathogenesis of hypoxic-ischemic encephalopathies mostly manifested in the periventricular region. We studied the vasomotor mode of actions of the peroxidation product 15-F(2t)-isoprostane (15-F(2t)-IsoP) (8-iso-prostaglandin F(2alpha)) on periventricular region during development.

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Augmented Vasoconstriction and Thromboxane Formation by 15-F <sub>2t</sub> -Isoprostane (8-Iso-Prostaglandin F <sub>2α</sub> ) in Immature Pig Periventricular Brain Microvessels

Augmented Vasoconstriction and Thromboxane Formation by 15-F 2t -Isoprostane (8-Iso-Prostaglandin F 2α ) in Immature Pig Periventricular Brain Microvessels

Augmented Vasoconstriction and Thromboxane Formation by 15-F _2t -Isoprostane (8-Iso-Prostaglandin F _2α ) in Immature Pig Periventricular Brain Microvessels