Is the Acetazolamide Test Valid for Quantitative Assessment of Maximal Cerebral Autoregulatory Vasodilation? | Zendy

Pierre Démolis | Zendy; Geneviève Florence | Zendy; Lionel Thomas | Zendy; Yves R. Tran Dinh | Zendy; JeanFrançois Giudicelli | Zendy; Jacques Seylaz | Zendy

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Is the Acetazolamide Test Valid for Quantitative Assessment of Maximal Cerebral Autoregulatory Vasodilation?

Author(s) -

Pierre Démolis,

Geneviève Florence,

Lionel Thomas,

Yves R. Tran Dinh,

JeanFrançois Giudicelli,

Jacques Seylaz

Publication year - 2000

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.31.2.508

Subject(s) - medicine , acetazolamide , vasodilation , cardiology , cerebral blood flow , cerebral circulation , anesthesia

The cerebral vasodilating effect of acetazolamide (ACZ) injection has been used as an index of the autoregulatory vasodilation (or cerebral perfusion reserve). The question of whether the ACZ test assesses the maximal autoregulatory vasodilating capacity is not definitely resolved. The effects of ACZ injection on this reserve at a dose producing maximal vasodilation have never been evaluated and may help to resolve this problem.

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