Genetic Predisposition to Stroke in Relatives of Hypertensives
Author(s) -
Michael Nicolaou,
Anita L. DeStefano,
Haralambos Gavras,
L. Adrienne Cupples,
Athanasios Manolis,
Clinton T. Baldwin,
Lindsay A. Farrer
Publication year - 2000
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.31.2.487
Subject(s) - medicine , stroke (engine) , proband , family aggregation , diabetes mellitus , odds ratio , family history , cohort , logistic regression , disease , pediatrics , endocrinology , mechanical engineering , biochemistry , chemistry , engineering , mutation , gene
The genetic basis of stroke is poorly understood. We evaluated patterns of familial aggregation of hypertension and stroke to test the hypothesis that inherited susceptibility to these disorders may be determined by a common set of factors.
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