Significant Association of Atrial Vulnerability With Atrial Septal Abnormalities in Young Patients With Ischemic Stroke of Unknown Cause | Zendy

Karine Berthet | Zendy; Thomas Lavergne | Zendy; Ariel Cohen | Zendy; L Guize | Zendy; MarieGermaine Bousser | Zendy; JeanYves Le Heuzey | Zendy; Pierre Amarenco | Zendy

Open Access

Significant Association of Atrial Vulnerability With Atrial Septal Abnormalities in Young Patients With Ischemic Stroke of Unknown Cause

Author(s) -

Karine Berthet,

Thomas Lavergne,

Ariel Cohen,

L Guize,

MarieGermaine Bousser,

JeanYves Le Heuzey,

Pierre Amarenco

Publication year - 2000

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.31.2.398

Subject(s) - medicine , atrial fibrillation , patent foramen ovale , cardiology , stroke (engine) , paradoxical embolism , embolism , odds ratio , thrombus , migraine , mechanical engineering , engineering

Atrial septal abnormalities have been associated with cryptogenic ischemic stroke in young patients, but the causal link has not yet been established. Paradoxical embolism is considered the most likely mechanism but is rarely proven. It can be hypothesized that, in those patients, paroxysmal atrial arrhythmias, potentially favored by the anatomic abnormalities, can be another cause of thrombus formation and subsequent embolism to the brain. In this study we assessed the relationship between atrial vulnerability, reflecting arrhythmogenic properties of the atria, and atrial septal abnormalities in young patients with cryptogenic ischemic stroke.

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