Selfotel in Acute Ischemic Stroke
Author(s) -
Stephen M. Davis,
Kennedy R. Lees,
Gregory W. Albers,
HansChristoph Diener,
S. Markabi,
Goeril Karlsson,
John W. Norris
Publication year - 2000
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.31.2.347
Subject(s) - medicine , stroke (engine) , placebo , ischemic stroke , neuroprotection , randomized controlled trial , clinical trial , barthel index , acute stroke , anesthesia , physical therapy , ischemia , rehabilitation , mechanical engineering , alternative medicine , pathology , engineering , tissue plasminogen activator
Based on neuroprotective efficacy in animal models, we evaluated the N-methyl D-aspartate antagonist Selfotel in patients with ischemic stroke, after doses up to 1.5 mg/kg were shown to be safe in phase 1 and phase 2a studies.
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