Differences in Vulnerability to Permanent Focal Cerebral Ischemia Among 3 Common Mouse Strains | Zendy

Arshad Majid | Zendy; Yong Y. He | Zendy; Jeffrey M. Gidday | Zendy; Stuart S. Kaplan | Zendy; Ernesto R. Gonzales | Zendy; T. S. Park | Zendy; Joseph D. Fenstermacher | Zendy; Ling Wei | Zendy; Dennis W. Choi | Zendy; Chung Y. Hsu | Zendy

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Differences in Vulnerability to Permanent Focal Cerebral Ischemia Among 3 Common Mouse Strains

Author(s) -

Arshad Majid,

Yong Y. He,

Jeffrey M. Gidday,

Stuart S. Kaplan,

Ernesto R. Gonzales,

T. S. Park,

Joseph D. Fenstermacher,

Ling Wei,

Dennis W. Choi,

Chung Y. Hsu

Publication year - 2000

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.31.11.2707

Subject(s) - medicine , ischemia , stroke (engine) , vulnerability (computing) , cardiology , mechanical engineering , computer security , computer science , engineering

Genetically engineered mice are used to study the role of single genes in cerebral ischemia, but inherent, strain-dependent differences in neuronal vulnerability may affect experimental end points. To examine this possibility, tissue injury resulting from focal ischemia and its relationship to cerebral hemodynamics were determined in 3 common mutant mouse strains.

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