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Safety and Cost of Low-Molecular-Weight Heparin as Bridging Anticoagulant Therapy in Subacute Cerebral Ischemia
Author(s) -
Mary Kalafut,
Rohina Gandhi,
Chelsea S. Kidwell,
Jeffrey L. Saver
Publication year - 2000
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.31.11.2563
Subject(s) - medicine , heparin , bridging (networking) , anticoagulant therapy , low molecular weight heparin , ischemia , anesthesia , intensive care medicine , cardiology , computer network , computer science
Anticoagulation with intravenous unfractionated heparin (IVUH) while awaiting therapeutic oral anticoagulant levels is a common practice in patients with acute and subacute cerebral ischemia. A promising alternative strategy is to use bridging subcutaneous low-molecular-weight heparin (LMWH), which may have a favorable risk-benefit profile compared with IVUH and may permit earlier discharge with completion of transition to warfarin therapy as an outpatient.

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