Spinal Cord Ischemia | Zendy

Loı̈c Lang-Lazdunski | Zendy; Kohji Matsushita | Zendy; Lorenz Hirt | Zendy; Christian Waeber | Zendy; JeanPaul G. Vonsattel | Zendy; Michael A. Moskowitz | Zendy

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Spinal Cord Ischemia

Author(s) -

Loı̈c Lang-Lazdunski,

Kohji Matsushita,

Lorenz Hirt,

Christian Waeber,

JeanPaul G. Vonsattel,

Michael A. Moskowitz

Publication year - 2000

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.31.1.208

Subject(s) - medicine , spinal cord , paraplegia , ischemia , anesthesia , lumbar arteries , lumbar spinal cord , femoral artery , lumbar , anatomy , cardiology , surgery , psychiatry

Spinal cord ischemia with resulting paraplegia is a devastating complication of thoracoabdominal aortic surgery. Experimental models of spinal cord ischemia have been developed in primate, dog, pig, rabbit, and rat with variable reproducibility, but none has been developed in mouse. Because genetically engineered mice have become important to examine the impact of specific genes in ischemic pathophysiology, we sought to develop a reproducible mouse model of spinal cord ischemia.

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