Ovariectomy Exacerbates and Estrogen Replacement Attenuates Photothrombotic Focal Ischemic Brain Injury in Rats | Zendy

Kenji Fukuda | Zendy; Hiroshi Yao | Zendy; Setsuro Ibayashi | Zendy; Tatsuo Nakahara | Zendy; Hideyuki Uchimura | Zendy; Masatoshi Fujishima | Zendy

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Ovariectomy Exacerbates and Estrogen Replacement Attenuates Photothrombotic Focal Ischemic Brain Injury in Rats

Author(s) -

Kenji Fukuda,

Hiroshi Yao,

Setsuro Ibayashi,

Tatsuo Nakahara,

Hideyuki Uchimura,

Masatoshi Fujishima

Publication year - 2000

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.31.1.155

Subject(s) - ovariectomized rat , medicine , estrogen , endocrinology , cerebral blood flow , estradiol valerate , sham surgery , ischemia , middle cerebral artery , pathology , alternative medicine

We previously reported the infarct volumes in female spontaneously hypertensive rats (SHR) to be significantly smaller than those in male SHR. The purpose of the present study was to determine whether estrogen is responsible for the sex difference in ischemic vulnerability in SHR.

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