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Measurement of Initial N- Acetyl Aspartate Concentration by Magnetic Resonance Spectroscopy and Initial Infarct Volume by MRI Predicts Outcome in Patients With Middle Cerebral Artery Territory Infarction
Author(s) -
Anthony Pereira,
Dawn E. Saunders,
Victoria L. Doyle,
J Martin Bland,
Franklyn A. Howe,
John R. Griffiths,
Martin M. Brown
Publication year - 1999
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.30.8.1577
Subject(s) - medicine , metabolite , infarction , middle cerebral artery , magnetic resonance imaging , stroke (engine) , nuclear medicine , cerebral infarction , in vivo magnetic resonance spectroscopy , voxel , cardiology , myocardial infarction , radiology , ischemia , mechanical engineering , engineering
(1)H MR spectroscopy can be used to study biochemical changes occurring in the brain in stroke. We used it to examine the relationship between metabolite concentration (N-acetyl aspartate [NAA], lactate, cholines and creatines), size of infarct, clinical deficit, and 3-month clinical outcome in patients with middle cerebral artery (MCA) territory infarction.

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