Elevated Anticardiolipin Antibody Titer Is a Stroke Risk Factor in a Multiethnic Population Independent of Isotype or Degree of Positivity
Author(s) -
Stanley Tuhrim,
Jacob H. Rand,
Xiao-Xuan Wu,
Jesse Weinberger,
Deborah Horowitz,
Martin E. Goldman,
James Godbold
Publication year - 1999
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.30.8.1561
Subject(s) - medicine , stroke (engine) , odds ratio , titer , population , risk factor , gastroenterology , immunology , atrial fibrillation , myocardial infarction , antibody , mechanical engineering , environmental health , engineering
Previous studies have produced conflicting results regarding the putative association between anticardiolipin antibodies (aCL) and infarction in the general stroke population. These inconsistencies may be a function of sample size and methodological differences among the studies. The purpose of the present study, the largest case-control study of this issue to date, was to assess aCL status as an independent risk factor for ischemic stroke in a multiethnic, urban population.
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