Open AccessInfluence of Platelet-Activating Factor on Cerebral Microcirculation in Rats
Author(s) -
Eberhard Uhl,
Sven Pickelmann,
Frank Röhrich,
A. Baethmann,
L. Schürer
Publication year - 1999
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.30.4.880
Subject(s) - platelet activating factor , medicine , microcirculation , platelet , endothelium , circulatory system , shock (circulatory) , cerebral circulation , intravital microscopy , anesthesia , endocrinology
Platelet-activating factor (PAF) is involved in the development of secondary brain damage after ischemic and traumatic brain injury. On the basis of data from studies in peripheral organs, we hypothesized that PAF-mediated effects after cerebral injury could be secondary to alterations in cerebral microcirculation.
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