Blockade and Reversal of Endothelin-Induced Constriction in Pial Arteries From Human Brain | Zendy

Lisa N. Pierre | Zendy; Anthony P. Davenport | Zendy

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Blockade and Reversal of Endothelin-Induced Constriction in Pial Arteries From Human Brain

Author(s) -

Lisa N. Pierre,

Anthony P. Davenport

Publication year - 1999

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.30.3.638

Subject(s) - vasoconstriction , medicine , electrical impedance myography , endothelin receptor , vasospasm , constriction , cerebral arteries , endothelin 1 , receptor , endocrinology , agonist , nimodipine , antagonist , anesthesia , subarachnoid hemorrhage , vasodilation , calcium

Substantial evidence now implicates endothelin (ET) in the pathophysiology of cerebrovascular disorders such as the delayed vasospasm associated with subarachnoid hemorrhage and ischemic stroke. We investigated the ET receptor subtypes mediating vasoconstriction in human pial arteries.

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