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Predictors of Brain Morphology for the Men of the NHLBI Twin Study
Author(s) -
Charles DeCarli,
Bruce L. Miller,
Gary E. Swan,
T. Reed,
Philip A. Wolf,
Jessica R. Garner,
Lisa M. Jack,
Dorit Carmelli
Publication year - 1999
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.30.3.529
Subject(s) - medicine , cardiology , atrophy , stroke (engine) , blood pressure , brain size , orthostatic vital signs , vascular disease , white matter , prospective cohort study , physical examination , magnetic resonance imaging , radiology , mechanical engineering , engineering
Cross-sectional studies show that cerebrovascular risk factors are associated with increased brain atrophy, accumulation of abnormal cerebral white matter signals, and clinically silent stroke. We extend these findings by examining the relationship between midlife cerebrovascular risk factors and later-life differences in brain atrophy, amount of abnormal white matter, and stroke on MRI.

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